Investigating Serotonin Dynamics and Simulating Effects of Antidepressants Using Variation in Enzyme Expression
January 23, 2024
Research JournalBy Alexander Diefes
Duke University
doi.org/10.55894/dv2.21
Synopsis
Depression is often treated with selective serotonin reuptake inhibitors (SSRIs), but some patients do not show improvements in their symptoms while taking them. Using a mathematical model of serotonin, we simulate the effects of various antidepressants and predict which factors may influence SSRI success.